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In a Phase 2b study in people with type 2 diabetes and obesity over 54 weeks, treatment with cotadutide at doses of 100-300 g daily improved some non-invasive markers of NAFLD such as transaminase levels, the FIB-4 index, fatty liver disease fibrosis score (NFS) and fatty liver index (FLI) but fatty liver disease was not assessed directly with liver biopsy

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Moreover, ADPN directly stimulates lipolysis and mitigates fat accumulation, contributing to obesity reduction [154]

Under the new deal, Hims serves as a major digital distributor for Wegovy (including the injectable and the newer oral "Wegovy Pill") and Ozempic