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The most commonly reported adverse events associated with the use of dihydroergotamine mesylate nasal spray during placebo-controlled, double-blind studies for the treatment of migraine headache and not reported at an equal incidence by placebo-treated patients were rhinitis, altered sense of taste, application site reactions, dizziness, nausea, and vomiting

Psychiatry 13 , 898600 (2022)

Flouri et al

However, clinical research commonly tests doses ranging from 250 to 600 milligrams per day, with the most effective results often observed at 500600 milligrams daily taken consistently for at least one to two months

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