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These structures were then subjected to energy minimization using the Gaussian16 55 software package, which optimized the geometries to ensure that the pAcF had the most stable conformations before integration into Rosetta

Why This Matters This research shifts our understanding of GLP-1s from "weight loss drugs with side benefits" to targeted metabolic therapies

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Additionally, a further follow-up study was conducted in patients with poor T2DM control and found a significant 31% reduction in LFC in patients treated with Lira