They found that TMAO was linked to heart disease, and that L-carnitine consumption led to TMAO production but only in people with certain gut microbes
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Once someone has done all the right things for nutrition, fitness, sleep, stress management, and frailty prevention, then having a conversation about adding a pharmacologic option for longevity or optimization becomes appropriate. The Takeaway GLP-1 medications, like semaglutide and tirzepatide, were originally developed for diabetes, but researchers are now exploring if they may extend lifespan and help people maintain good health for a longer period of time
However, to maintain optimal B12 levels and sustained benefits, regular injections are often necessary, typically every few weeks or months
& Mattevi, A