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A review published in Nutrients which discusses how curcumin supplementation has been studied for changes in body measurements in adults with overweight (1)

Patients with nutritional compromise face increased risk for systemic inflammatory response syndrome (SIRS) with IV administration

Results depend on consistent use as part of an ongoing routine

They see them as pharmacologically active, unapproved, and too risky for sport

Taking more than the recommended dose of certain products over long periods including those that contain iron or fat-soluble vitamins such as vitamins A, D, E, and K may also lead to very serious side effects