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0.610.83), with a modest decrease in heart failure hospitalization (HR 0.85

The tonicity of an aqueous solution of the water-soluble composition of the present invention should be within the tolerable range when administered and is adjusted, for example, by isotonizing agents such as sodium chloride and mannitol

However, the amount of bone loss varies by population and skeletal site.7 Severe Adverse Effects A more severe adverse effects associated with the use of GLP-1 agonist drugs is pancreatitis

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