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This finding highlights concerns regarding its possible adverse effects on healthy tissues, underscoring the need for careful dose optimization and further investigation into its safety profile

Animals were allocated to experimental groups using a random number generator, and investigators conducting the experiments and analyses were blinded to group allocation through the use of independent codes to minimize potential bias

Acknowledgements This work was supported, in part, by funding from the Alexander von Humboldt Foundation, the European Research Council (ERC) AdG HypoFlam no

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