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Since semaglutide slows down the rate at which food leaves your stomach, you may experience side effects such as nausea and vomiting

3.4 Evaluation of Semaglutide Exposures and Bioavailability Following Oral Administration in Subjects with T2D With or Without Upper GI Disease The re-estimated model based on data from the trial in 55 subjects with T2D with or without upper GI disease [21] included covariate factors for T2D and for upper GI disease