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If you ever experience sudden or severe symptoms such as swelling of the lips, face, or throat, difficulty breathing, or collapse, you must seek urgent medical help immediately by calling 999 or attending your nearest A&E

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Methylene blue should not be used in combination with certain psychiatric serotonin medications, during pregnancy or nursing or severe liver and kidney disease

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One case report describes the onset of dysphagia and gastroparesis in a patient with Crohns disease 2 months before developing Wernicke encephalopathy, which resolved with high dose thiamine (72)