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Evidence of a small diabetes signal should be framed against the larger heart-attack/stroke risk reduction in higher-risk patients

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In addition, they may have other modes of action, as causing oxidative stress, genetic susceptibility, and epigenetic modifications (e.g., DNA methylation, miRNA) ( Specifically, some studies have demonstrated that EDCs such as bisphenol A (BPA), di-2-ethylhexyl phthalate (DEHP), dibutyl phthalate (DBP), and pesticides exert some of their endocrine-disrupting activity by influencing methylation patterns