Interestingly, administration of the l-theaninecaffeine combination was associated with a significant decrease in reactivity of CEN compared to placebo in a cluster that included the bilateral middle and superior frontal, paracingulate and precentral gyri and the left inferior frontal gyrus (p = 0.007)
What the FDA briefing report said about the evidence
Reduces pain in muscles and joints Helps relieve tension headaches and soreness Get rapid relief from nausea and upset stomach
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a master transcriptional regulator integrating diverse cellular processes, including antioxidant responses, NADPH biosynthesis, autophagy, and mitochondrial biogenesis [133]
MCFAs also display antiviral and antibacterial activities and have a functional impact on the modulation of the gut microbiota during early infancy (17, 18), which is related to the maturation of the immune system and general health (19)
