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The CesAs terminal C domain is proposed to work in trans with the D- O -Leu-D-Ala peptide as donor and the hydroxy group of the CesB1 PCP-thioester bound L- O -Val, followed by CesB2 PCP-bound L-Val as nucleophilic acceptors 8

NKF KDOQI GUIDELINES KDOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification Figures Figure 1 Evidence Model for Stages in the Initiation and Progression of Chronic Kidney Disease and Therapeutic Interventions Figure 2 Incidence and Prevalence of End-Stage Renal Disease in the US Figure 3 Evidence Model for Stages in the Initiation and Progression of Cardiovascular Disease and Therapeutic Interventions Figure 4 Kidney Function Decline in Chronic Kidney Disease Figure 5 Creatinine Distribution: US Population Age 20 by Sex Figure 6 Cardiovascular Mortality in the General Population (NCHS) and in ESRD Treated by Dialysis (USRDS) Figure 7 Prevalence of Albuminuria and High Blood Pressure (%) in US Adults Age 20 Years, NHANES III, 1988-1994 Figure 8 Distribution of Albumin-to-Creatinine Ratio in US Men and Women, Age 20 Years: NHANES III, 1988-1994 Figure 9 GFR vs

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