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Nucleic acids research 45, D499D506 pmid:28053164 3

634 AAK1 inhibitor LX-9211: Junctional protein 2-associated kinase 1 (AAK1) is widely expressed in the brain and spinal cord and is a viable target for the treatment of neuropathic pain, and BMS-986176/LX-9211 is a novel class of bis(iso)aryl ethers that are highly selective, CNS-permeable, and potent AAK1 inhibitors

The immunoreacting protein bands were visualized after interacting with primary antibodies against cytochrome c, caspase-3, PARP, GSTA4-4 and Bcl-2

Molteni et al , 2004)

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