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Rarely these drugs may be associated with acute pancreatitis or cholelithiasis, although causal link is questionable

Category 2 is the problem bucket: substances the FDA says may present significant safety risks citing issues such as immunogenicity (the body forming antibodies against an injected peptide), impurities from synthesis, and thin human data

Some also report mild localised redness, small lumps, or temporary irritation

Symptoms do not improve after using over-the-counter antifungal treatments for the recommended duration

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