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Berberine Berberine is a Chinese medicinal herb

doi: 10.1016/j.fsi.2020.09.036 68 YaoT.LiL

Modulating Effect of the PI3-Kinase Inhibitor LY294002 on Cisplatin in Human Pancreatic Cancer Cells

Type 2 diabetes mellitus (DM2) affects a 13.8% of the Spanish population1 and its prevalence is expected to increase in the future.2 The presence of DM2 increases significantly the risk of cardiovascular events, chronic kidney disease (CKD), and premature death3,4 and as its prevalence increases it is expected to rise the incidence of microvascular and macrovascular complications.5 Until the last decade, the control of blood glucose, blood pressure, dyslipidemia, and the use of inhibitors of the renin-angiotensin system (iSRA) have been the only strategies available to reduce cardiovascular and renal risk in this population

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