The slowed gastric emptying from GLP-1 therapy could theoretically exacerbate inflammation or obstruction risk in active Crohn's, though controlled clinical data specific to this population remains limited
Hospitalized patients with T1DM and COVID-19 A population-based analysis from Belgium showed a similar risk of hospitalization in people with T1DM than in normoglycaemic individuals (0.21% versus 0.17%) 139
48 In the Tirzepatide as Compared with Semaglutide for the Treatment of Obesity (SURMOUNT-5) trial in adult participants with obesity but without T2DM, tirzepatide (10 mg or 15 mg) achieved greater weight loss compared with semaglutide (1.7 mg or 2.4 mg weekly dose): 20.2% (95% CI 21.4 to 19.1) versus -13.7% (95% CI 14.9 to 12.6) at week 72
Individual participant data will be shared in data sets in a de-identified/anonymized format
Signs of heat-related illness Signs of heat exhaustion can include: drop in blood pressure when exerting yourself dizziness nausea feeling faint sweating profusely moist, cool, or cold skin weak and rapid pulse headache muscle cramps The more severe condition, heatstroke, is a medical emergency
