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Avoiding alcohol and smoking for at least 24 hours also reduces stress on the liver

It inhibits tyrosinase, a key enzyme involved in melanin production, and it also shifts melanin synthesis towards lighter pheomelanin rather than darker eumelanin, contributing to brighter-looking skin. Mechanism of action on pigmentation Melanin is the pigment responsible for skin colour, and its overproduction contributes to tanning, dark spots, and uneven tone

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The formulation was well tolerated, and the study concluded that combining niacinamide and retinol within a complete skincare routineincluding hydration and photoprotectionis highly beneficial