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The 12-hour window allows stimulation followed by your body's natural response period

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31 Over the past 20 years, new GLP-1RAs with extended half-lives have proven to be highly effective treatments for T2D and even weight loss

J Clin Pharmacol 29:207211

The effects of GLP1RAs on alcohol intake have also been tested in nonhuman primates with longterm access to alcohol, where alcohol consumption was significantly reduced when treated with the GLP1RAs exenatide or liraglutide compared to placebo [59]