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Mult Scler (2017) 23(3):44755

Reconstitution refers to the process of dissolving a lyophilised (freeze-dried) powder into a liquid solution to prepare it for injection

The overexpression of arginine methyltransferase 5 (PRMT5) in solid and hematological tumors leads to the elevation of the methylation level of arginine residues on functionally related proteins in tumor cells, which affects cell cycle regulation, mRNA splicing, cell differentiation, signal transduction, and other physiological processes