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While GLP-1 RAs offer promising therapeutic outcomes, clinicians must address potential challenges, including gastrointestinal side effects, contraindications (e.g., pregnancy, severe GI disorders), and risks associated with improper compounding practices (48)(540)

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Franz diffusion cell studies comparing free GHK-Cu versus liposomal preparations document 5-fold greater dermal concentrations and 3-fold higher retention times for liposomal formulations

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