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Novel GLP-1-based Medications for Type 2 Diabetes and Obesity (Endocrine Reviews)

Lin Z, Chen C, Yang D, Ding J, Wang G, Ren H

Engineered butyrate-producing bacteria prevents high fat diet-induced obesity in mice

BPC-157 has a short plasma half-life (on the order of minutes intravenously ) but its systemic effect exceeds pharmacokinetics, the mechanism acts via signalling cascades and transcription factors