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"The freezing step in lyophilization: physico-chemical fundamentals, freezing methods, and consequences on process performance and quality attributes of biopharmaceuticals." European Journal of Pharmaceutics and Biopharmaceutics

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Full-length human growth hormone binds to growth hormone receptors distributed throughout the body, triggering a cascade of effects including stimulation of IGF-1 production in the liver, alterations in glucose and insulin metabolism, protein synthesis in muscle tissue, bone growth and remodeling, organ enlargement with prolonged use, and fluid retention

It was the first peptide of its kind, described by Cyril Bowers in 1984, and it is the parent compound behind GHRP-2, hexarelin, and ipamorelin