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When using any transdermal medication, patients should avoid applying a new patch to the same exact location for at least one to two weeks, or as specified in the product labeling

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doi: 10.1016/S22138587(22)000778 77 DahlDOnishiYNorwoodPHuhRBrayRPatelHet al

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So theyre a part of all the different things that were seeing, side effects and challenges for in the perimenopausal women