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Deficiency causes nerve dysfunction (numbness, balance issues) and can lead to irreversible damage

An association between soluble CD14 and anti-tissue transglutaminase IgG has also been described [112]

The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form

Effect of pharmacological modulators of NO/cGMP/K ATP signaling pathway on nicorandil mediated antinociceptive effect on cold allodynia induced by acetone in CCI rats Nicorandil administration (150 mg/kg, twice, 2 h interval, PO) significantly alleviated acetone cold allodynia at all tested time intervals (1.5, 3.5, 5.5 and 7.5 h after first nicorandil dose) manifested as significant decrease in the cumulative scores (P 0.05) (Fig

These cytoprotective pathways are also involved in development of drug resistance, hence their suppression might account for the extended drug sensitivity observed in AML cells after combined treatment