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doi: 10.1111/j.1749-6632.2012.06707.x

In a second double-blind RCT, KET 0.5 mg/kg IV bolus followed by a 30 min infusion of 0.25 mg/kg/h increased mood and serum brain-derived neurotrophic factor, which is a marker of major depressive disorders and treatment response (Jiang et al., 2016)

But its not true that there is no evidence

Insight into the essential role of the helicobacter pylori Hp1043 orphan response regulator: Genome-wide identification and characterization of the DNA-binding sites