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Conclusion Semaglutide is more than just a medication

Insulin glargine/lixisenatide fixed-ratio combination (iGlarLixi) vs fixed-ratio combination of insulin degludec/liraglutide (IDegLira) in uncontrolled type 2 diabetes: The LixiLan-G Trial. Diabetes Care, vol

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Twenty-nine participants in the placebo group and 34 in the semaglutide arm completed the trial, meeting the target sample size for the primary outcome analysis

Additionally, animal studies have suggested that GLP-1 receptors are present in brain regions involved in stress response, though the clinical significance of this in humans remains unclear