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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for chronic weight management, along with a reduced calorie diet and increased physical activity, for people with an initial body mass index (BMI) of: 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia)

All of these complications can be fatal

It is a dual agonist that stimulates both GLP-1 and GIP receptors

95% confidence interval, 13.9 to 9.0

Compounded versions are created by specialized pharmacies but dont undergo the same rigorous testing and quality control as other drugs that are FDA-approved