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However, stressors such as excessive temperature, pH, salinity, and chemical pollution might have a negative impact on them (Paz-Ferreiro and Fu, 2016)

S-adenosylmethionine (SAMe), an amino acid derivative important in liver metabolism, and extracts from milk thistle ( Silybum marianum ), have been investigated (alone and in combination) in dogs for their liver-protecting properties and are currently used as part of treatment for a variety of liver diseases in dogs

However, if your gut health is compromised or you have significant genetic variants, it may take several weeks to months of consistent support

no supplementation was performed at this time

Not commonly used for general supplementation due to cost and invasiveness