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Persistent/sustained hyperglycemia is perhaps the main consequence responsible for major organ damage, especially through destructive mechanisms involving activation of oxidative stress and promoting a pro-inflammatory response (Giacco and Brownlee, 2010)

GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) that declines with age

Additionally, it protects cells from damage caused by free radicals, thus promoting overall cellular health and function

Tretinoin also makes skin photosensitive, so daily use of broad-spectrum sunscreen is a must