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Amylin biology supports a genuine postprandial signature slower nutrient delivery, suppressed postprandial glucagon, reduced meal size and the cagrilintide-plus-semaglutide diabetes data are consistent with a maintained postprandial glucose benefit

Funding Statement The authors are supported by grants from the National Institute of Health (NIH/NCCIH)-(5R33AT010637-01A1 and 3R33 AT010637-02S1) and the Malcolm Feist Endowed Chair in Diabetes

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This decline affects sleep quality, circadian regulation, and downstream hormonal systems