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The preparation is standardised prior to use, allowing researchers to work with a consistent peptide composition and eliminating variability associated with solution preparation
Preclinical timelines run over weeks meaningful model-level changes appear across roughly weeks 412, not in the first days
The sulfur, oxygen, and nitrogen ligands that coordinate metals in enzymes will frequently bind non-native cofactors with affinities equal to or greater than those of the native cofactor
10.1007/s12029-021-00630-0 81 SalamaN
2023;228:152388 Nunes AF, Amaral JD, Lo AC, Fonseca MB, Viana RJ, Callaerts-Vegh Z, et al
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