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198 In the context of obesity, increased hepatic expression of the unconventional prefoldin RPB5 interactor (URI) has been shown to couple nutrient surplus with inflammation, leading to nonalcoholic steatohepatitis (NASH) and consequent HCC

Abstract Background/Objectives Although glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are highly effective for body weight reduction, there remains a critical unmet need for complementary strategies that drive selective fat loss and sustain long-term weight reduction

References Pasqua M, et al

has demonstrated hepatoprotective effects against the progression of nonalcoholic fatty liver disease (NAFLD) in rats

& Marco, J