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Patients should be informed about potential side effects of antiemetics, including QT prolongation with ondansetron

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First, while the effects of fatty acids in vitro and hyperlipidaemia in vivo were consistently observed at the level of Glp1r expression and signalling, the decrease in Gipr was not seen in vitro, and normalisation of circulating lipid levels did not improve the efficacy of D-GIP in db/db mice

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Clinical Efficacy and Safety Profile The combination of GIP, GLP-1, and glucagon receptor agonism makes Retatrutide exceptionally potent