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There is currently no evidence that GLP-1 agonists directly treat or reverse leptin resistance itself

(2) However, Gregg advises caution for individuals with certain health conditions, including Type 1 diabetes, or for those who are pregnant or breastfeeding (1)

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The American Diabetes Association defines diabetes Mellitus as a group of metabolic diseases characterized by hyperglycemia (high blood sugar) resulting from defects in insulin secretion, insulin action or both