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Many patients benefit from maintaining a low-FODMAP diet or other IBS-proven dietary modifications while adjusting to GLP-1, since the combination of slower gastric emptying and food triggers can compound bloating or urgency

Patients and clinicians should be aware that reflux-type symptoms are biologically plausible and have been reported in trial settings for this drug class, even if a definitive causal link has not been formally established for retatrutide specifically

However, a recent Segal analysis found most patients were already using another established diabetes drug, which suggests this strategy may not be as effective as others in managing costs

My work has always been about translating evidence, not monetising hype

If supplementation is discontinued, the skin may gradually return to its original tone over time