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Vit-E could effectively prevent ferroptosis by reducing the Fe 3+ center to inactive Fe 2+ in lipoxygenase (LOX), thereby inhibit enzyme activity of LOX

Therefore, they require to be broken down to the active isothiocyanate (ITCs) by the enzyme myrosinase either through chewing or mild cooking (Herr and Buchler, 2010)

2000;275 doi: 10.1074/jbc.M907022199

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