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[DOI] [PubMed] [Google Scholar] 83.Del Bo C., Perna S., Allehdan S., et al

With respect to endothelial function, evidence to support the concept that eNOS uncoupling contributes to endothelial dysfunction was obtained by experiments demonstrating that supplementation with BH 4 or the BH 4 precursor sepiapterin was able to improve endothelial dysfunction in patients with hypertension