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Cracking the PROTAC Permeability Barrier: CD36-Mediated Endocytosis as a Potential Breakthrough 2025-12-03 In recent years, proteolysis-targeting chimeras (PROTACs) have shown tremendous promise in targeting "undruggable" proteins

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Exploring the molecular mechanisms underlying DSIPs effects, which could pave the way for the development of optimized analogs or targeted therapies

For the international research community, this limits direct access to the approved product