These antioxidant enzymes include: Superoxide dismutase (SOD): uses copper, zinc, and manganese as cofactors (there is more than one SOD enzyme)
Other causes, such as irritable bowel syndrome (IBS),14 inflammatory bowel disease (IBD), colonic neoplasms, and hyperplastic polyps, could also contribute to the onset of MC.13,15 Some studies show that MC may be connected to the use of non-steroidal anti-inflammatory drugs (NSAIDs),16 vitamin E (VE) deficiency, the intake of unsaturated fatty acids,17 environmental factors,18 family history,3 psoriasis19 and Rett syndrome.20 Feces stasis also plays an important role in the pathogenesis of MC
Expending the known reduced species (NADH+, reduced glutathione, etc.) to neutralize the deleterious compounds weakens the organisms capacity to combat further oxidative stress
Unlike caffeine or amphetamines, these molecules generally do not produce acute stimulation
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