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Key results The results were dose-dependent and remarkable at every level: 1mg: Approximately 8.7% weight loss 4mg: Approximately 17.1% weight loss 8mg: Approximately 22.8% weight loss 12mg: Approximately 24.2% weight loss Placebo: Approximately 2.1% weight loss The 24.2% weight loss at 12mg over 48 weeks was unprecedented

However, lesions arising on the soles and within the nail unit can be difficult to recognise leading to delays in diagnosis

Trx1 and Trx2 share 35% sequence homology and exhibit similar catalytic properties in vitro [10]

doi: 10.1016/j.jnutbio.2010.07.009 172 ParkJSLeeEJLeeJCKimWKKimHS

and step 3: stirring to dissolve and clarify the prepared solution, adding water for injection to full amount, and adjusting pH to 7.0 with 10% sodium hydroxide solution