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Concerning patients with AIT, the current Guidelines do not recommend Se replacement during pregnancy [69], while there is a lack of randomized control trials (RCTs) to determine the safety and efficacy of Se supplementation in pregnancy at high risk for adverse events, including miscarriage, preeclampsia, preterm delivery, and fetal death

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He told MNT that he hopes these findings dont dampen enthusiasm for the broader line of inquiry. In particular, he told us that he is encouraged by the potential of GLP-1 agonists when combined with lifestyle modification as a preventive strategy to reduce dementia risk before symptoms emerge, where the biology may be far more modifiable. Although the Evoke studies, on paper, failed, there is still hope

The antidiabetic effect of the microbially produced GLP-1 was confirmed with Lactobacillus plantarum WCFS1 in db/db mice and Lactobacillus plantarum -pMG36e-GLP-1 in a rhesus monkey model [311,313]

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