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If you also have erection or libido changes on these drugs, our companion guide on GLP-1 drugs and mens sexual health covers that side of the picture, and our explainer on reading your semen analysis results shows what a real change would look like on paper

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Heres a quick guide to some of the most notable published and ongoing trials in the STEP series: STEP-1 is the first and largest STEP trial, involving 1961 nondiabetic but obese or overweight individuals