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Many patients who fall below a 30 BMI kg/m2 after one year on therapy might be good candidates to step down to less expensive therapies if their labs and clinical picture agree

Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma

"Dual GIP and GLP-1 receptor agonist tirzepatide alleviates hepatic steatosis and modulates gut microbiota and bile acid metabolism in diabetic mice" Int Immunoph PubMed Tirzepatide is a dual agonist of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors and is a promising therapeutic option for type 2 diabetes mellitus (T2DM)