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Any other effect can be considered as a pleiotropic, off-target effect, or in the case of unwanted actions, adverse effects ( Figure 1 )

Maldifassi MC, Martn-Snchez C, Atienza G, Cedillo JL, Arnalich F, Bordas A, Zafra F, Gimnez C, Extremera M, Renart J, Montiel C (2018) Interaction of the 7-nicotinic subunit with its human-specific duplicated dup7 isoform in mammalian cells: relevance in human inflammatory responses

It states that medication selection should be individualized based on patient factors, not driven by formulary economics alone

Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription

2024 June 12