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This gut hormone triggers multiple physiological responses that play a role in regulating body weight, such as releasing insulin to help control blood sugar levels, slowing stomach emptying (so we feel fuller for longer) and even telling the brains hunger centres to suppress appetite

Doses above 100 mcg/day increase anabolic signaling but also elevate the risk of hypoglycemia, connective tissue hypertrophy, and prolonged suppression of endogenous GH production

Effects of metformin on endometrial cancer: systematic review and meta-analysis