Personal outcomes depend on factors such as starting weight, metabolism, medical history, and how well side effects are tolerated
Berger MM, Shenkin A, Schweinlin A, Amrein K, Augsburger M, Biesalski HK et al (2022) ESPEN micronutrient guideline
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Therefore, obesity can lead to a high risk of cardiovascular diseases, type 2 diabetes mellitus (DM2), hypertension, and some types of cancer
No Pediatric Research Equity Act (PREA) requirement has compelled Novo Nordisk to conduct trials in children aged 6 to 11 for this specific indication, though the company's ClinicalTrials.gov profile lists ongoing pediatric pharmacokinetic studies for semaglutide in younger populations