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Many mutational and structural studies have been carried out on the mu and alpha classes of GST to elucidate the reaction mechanism, whereas knowledge about the pi class is still limited

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In the study, researchers analyzed patient records from more than 600,000 people in a Department of Veterans Affairs database

Authors' hypothesis reveals that the loss of this kind of endogenous inhibitory signal might contribute to allodynia and central sensitization, with the subsequent development of chronic pain