Diminishing returns and more side effects are reported above 150 mg
In addition to this, P4HA1 immune-modulatory role in cancer has been only recently analysed in different cancer types where its increase associated with worse cancer prognosis and lower overall survival, correlates with an immunosuppressive TME and reduced anti-tumoral response [24, 25, 64]
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This antioxidant network is essential for protecting the liver, supporting detoxification, and maintaining the structural integrity of tissues exposed to chronic inflammation
