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Interestingly, this effect is augmented by the presence of hyperglycemia, indicating that comorbid diabetes may enhance the proatherogenic phenotype of G6PD-d

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Mast cell serine proteases, tryptase, chymase, and carboxypeptidase, further contribute to mast cell degranulation (161)

Most patients have upper abdominal discomfort, fullness, gastric ulcer, and precancerous lesions [14]

Patients on high doses for extended periods should be monitored by their healthcare provider for signs of adrenal insufficiency