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[2] [3] However, in April 2025, Pfizer announced it would abandon further development of danuglipron due to unpredictable liver toxicity

Patients with polycythemia vera a blood disorder involving overproduction of red blood cells face additional risks since B12 stimulates red blood cell production

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While blood sugar remains important, it has become increasingly clear that cardiovascular disease is the leading cause of death in people with diabetes